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1

Short-course antibiotic therapy for critically ill patients treated for postoperative intra-abdominal infection: the DURAPOP randomised clinical trial

Montravers, Philippe, Tubach, Florence, Lescot, Thomas, Veber, Benoit, Esposito-Farèse, Marina, Seguin, Philippe, Paugam, Catherine, Lepape, Alain, Meistelman, Claude, Cousson, Joel, Tesniere, Antoine

Journal:

Intensive Care Medicine

Year:

2018

Language:

english

File:

PDF, 1.17 MB

english, 2018

2

European intensive care physicians’ experience of infections due to antibiotic-resistant bacteria

Lepape, Alain, Jean, Astrid, De Waele, Jan, Friggeri, Arnaud, Savey, Anne, Vanhems, Philippe, Gustin, Marie Paule, Monnet, Dominique L., Garnacho-Montero, José, Kohlenberg, Anke

Journal:

Antimicrobial Resistance and Infection Control

Year:

2020

Language:

english

File:

PDF, 1.12 MB

english, 2020

3

Drug incompatibilities in intravenous therapy: evaluation and proposition of preventive tools in intensive care and hematology units

Maison, Ophélie, Tardy, Cléa, Cabelguenne, Delphine, Parat, Stéphanie, Ducastelle, Sophie, Piriou, Vincent, Lepape, Alain, Lalande, Laure

Journal:

European Journal of Clinical Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.96 MB

english, 2018

4

Comparison of four skin preparation strategies to prevent catheter-related infection in intensive care unit (CLEAN trial): a study protocol for a randomized controlled trial

Véronique Goudet, Jean-François Timsit, Jean-Christophe Lucet, Alain Lepape…

Journal:

Year:

2013

Language:

english

File:

PDF, 239 KB

english, 2013

5

Development and validation of a questionnaire for quantitative assessment of perceived discomforts in critically ill patients

Pierre Kalfon, Olivier Mimoz, Pascal Auquier, Anderson Loundou, Rémy Gauzit, Alain Lepape, Jean Laurens, Bernard Garrigues, Thierry Pottecher, Yannick Mallédant

Journal:

Intensive Care Medicine

Year:

2010

Language:

english

File:

PDF, 220 KB

english, 2010

6

De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicenter non-blinded randomized noninferiority trial

Leone, Marc, Bechis, Carole, Baumstarck, Karine, Lefrant, Jean-Yves, Albanèse, Jacques, Jaber, Samir, Lepape, Alain, Constantin, Jean-Michel, Papazian, Laurent, Bruder, Nicolas, Allaouchiche, Bernard,

Journal:

Intensive Care Medicine

Year:

2014

Language:

english

File:

PDF, 446 KB

english, 2014

7

Trends of Incidence and Risk Factors of Ventilator-Associated Pneumonia in Elderly Patients Admitted to French ICUs Between 2007 and 2014

Dananché, Cédric, Vanhems, Philippe, Machut, Anaïs, Aupée, Martine, Bervas, Caroline, L’Hériteau, François, Lepape, Alain, Lucet, Jean-Christophe, Stoeckel, Vincent, Timsit, Jean-François, Berger-Carb

Journal:

Critical Care Medicine

Year:

2018

File:

PDF, 301 KB

2018

8

Messenger RNA expression of major histocompatibility complex class II genes in whole blood from septic shock patients*

Pachot, Alexandre, Monneret, Guillaume, Brion, Aurélie, Venet, Fabienne, Bohé, Julien, Bienvenu, Jacques, Mougin, Bruno, Lepape, Alain

Journal:

Critical Care Medicine

Year:

2005

Language:

english

File:

PDF, 677 KB

english, 2005

9

A strategy to build and validate a prognostic biomarker model based on RT-qPCR gene expression and clinical covariates

Tournoud, Maud, Larue, Audrey, Cazalis, Marie-Angelique, Venet, Fabienne, Pachot, Alexandre, Monneret, Guillaume, Lepape, Alain, Veyrieras, Jean-Baptiste

Journal:

BMC Bioinformatics

Year:

2015

Language:

english

File:

PDF, 2.95 MB

english, 2015

10

Innovative Therapeutic Strategies for Restoring Lymphocyte Functions in Septic Patients

Turrel, Fanny, Guignant, Caroline, Venet, Fabienne, Lepape, Alain, Monneret, Guillaume

Journal:

Inflammation & Allergy - Drug Targets

Year:

2008

Language:

english

File:

PDF, 107 KB

english, 2008

11

Endogenous Retroviruses Transcriptional Modulation After Severe Infection, Trauma and Burn

Tabone, Olivier, Mommert, Marine, Jourdan, Camille, Cerrato, Elisabeth, Legrand, Matthieu, Lepape, Alain, Allaouchiche, Bernard, Rimmelé, Thomas, Pachot, Alexandre, Monneret, Guillaume, Venet, Fabienn

Journal:

Frontiers in Immunology

Year:

2019

File:

PDF, 4.00 MB

2019

12

Analytical Requirements for Measuring Monocytic Human Lymphocyte Antigen DR by Flow Cytometry: Application to the Monitoring of Patients with Septic Shock

Monneret, Guillaume, Elmenkouri, Nadia, Bohe, Julien, Debard, Anne-Lise, Gutowski, Marie-Claude, Bienvenu, Jacques, Lepape, Alain

Journal:

Clinical Chemistry

Year:

2002

File:

PDF, 133 KB

2002

13

Production of Proinflammatory Cytokines and Cytokines Involved in the TH1/TH2 Balance Is Modulated by Pentoxifylline

Bienvenu, Jacques, Doche, Christophe, Gutowski, Marie-Claude, Lenoble, Michèle, Lepape, Alain, Perdrix, Jean-Pierre

Journal:

Journal of Cardiovascular Pharmacology

Year:

1995

File:

PDF, 422 KB

1995

14

Dynamic LTR retrotransposon transcriptome landscape in septic shock patients

Mommert, Marine, Tabone, Olivier, Guichard, Audrey, Oriol, Guy, Cerrato, Elisabeth, Denizot, MÃ©lanie, Cheynet, ValÃ©rie, Pachot, Alexandre, Lepape, Alain, Monneret, Guillaume, Venet, Fabienne, Brenge

Journal:

Year:

2020

Language:

english

File:

PDF, 1.76 MB

english, 2020

15

Increased circulating regulatory T cells (CD4+CD25+CD127−) contribute to lymphocyte anergy in septic shock patients

Fabienne Venet, Chun-Shiang Chung, Hakim Kherouf, Anne Geeraert, Chistophe Malcus, Françoise Poitevin, Julien Bohé, Alain Lepape, Alfred Ayala, Guillaume Monneret

Journal:

Intensive Care Medicine

Year:

2009

Language:

english

File:

PDF, 354 KB

english, 2009

16

Possible involvement of multiple cytochrome P450S in fentanyl and sufentanil metabolism as opposed to alfentanil

Jérôme Guitton, Thierry Buronfosse, Michel Désage, Alain Lepape, Jean-Louis Brazier, Philippe Beaune

Journal:

Biochemical Pharmacology

Year:

1997

Language:

english

File:

PDF, 845 KB

english, 1997

17

Soluble human leukocyte antigen-G5 in septic shock: Marked and persisting elevation as a predictor of survival

Monneret, Guillaume, Voirin, Nicolas, Krawice-Radanne, Irène, Bohé, Julien, Lepape, Alain, Rouas-Freiss, Nathalie, Carosella, Edgardo D.

Journal:

Critical Care Medicine

Year:

2007

Language:

english

File:

PDF, 303 KB

english, 2007

18

Clinical and Therapeutic Features of Nonpostoperative Nosocomial Intra-abdominal Infections

Montravers, Philippe, Chalfine, Annie, Gauzit, Remy, Lepape, Alain, Pierre Marmuse, Jean, Vouillot, Corinne, Martin, Claude

Journal:

Annals of Surgery

Year:

2004

Language:

english

File:

PDF, 295 KB

english, 2004

19

Poor adherence to guidelines for preventing central line-associated bloodstream infections (CLABSI): results of a worldwide survey

Valencia, Cristina, Hammami, Naïma, Agodi, Antonella, Lepape, Alain, Herrejon, Eduardo Palencia, Blot, Stijn, Vincent, Jean-Louis, Lambert, Marie-Laurence

Journal:

Antimicrobial Resistance and Infection Control

Year:

2016

Language:

english

File:

PDF, 417 KB

english, 2016

20

Relevance of blood cultures in acute pyelonephritis in a single-center retrospective study

Ledochowski, Stanislas, Abraham, Paul-Samuel, Jacob, Xavier, Dumitrescu, Oana, Lina, Gérard, Lepape, Alain, Piriou, Vincent, Wallet, Florent, Friggeri, Arnaud

Journal:

Internal and Emergency Medicine

Year:

2015

Language:

english

File:

PDF, 247 KB

english, 2015

21

DYNAMIC TRANSCRIPTIONAL DOWN-REGULATION OF HLA-DR- RELATED GENES IN PERIPHERAL BLOOD OF SEPTIC SHOCK PATIENTS

Pachot, Alexandre, Monneret, Guillaume, Mougin, Bruno, Lepape, Alain

Journal:

Year:

2004

File:

PDF, 150 KB

2004

22

Early and dynamic changes in gene expression in septic shock patients: a genome-wide approach

Marie-Angélique Cazalis,Alain Lepape…

Journal:

Intensive Care Medicine Experimental

Year:

2014

Language:

english

File:

PDF, 2.09 MB

english, 2014

23

Elevated soluble IL-7 receptor concentration in non-survivor ICU patients

Peronnet, Estelle, Mouillaux, Julie, Monneret, Guillaume, Gallet-Gorius, Emmanuelle, Blein-Henry, Sophie, Lepape, Alain, Textoris, Julien, Venet, Fabienne

Journal:

Intensive Care Medicine

Year:

2016

Language:

english

File:

PDF, 1.24 MB

english, 2016

24

Correction to: ECDC definitions and methods for the surveillance of healthcare-associated infections in intensive care units

Plachouras, Diamantis, Lepape, Alain, Suetens, Carl

Journal:

Intensive Care Medicine

Year:

2018

Language:

english

File:

PDF, 648 KB

english, 2018

25

Qualité des soins, gestion des risques et infections nosocomiales

Journal:

Year:

2007

Language:

french

File:

PDF, 535 KB

french, 2007

26

Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients

Caroline Guignant, Alain Lepape, Xin Huang, Hakim Kherouf, Laure Denis, Françoise Poitevin, Christophe Malcus, Aurélie Chéron, Bernard Allaouchiche, François Gueyffier, Alfred Ayala, Guillaume Monnere

Journal:

Critical Care (BioMed Central)

Year:

2011

Language:

english

File:

PDF, 742 KB

english, 2011

27

A dynamic view of mHLA-DR expression in management of severe septic patients

Guillaume Monneret,Alain Lepape,Fabienne Venet

Journal:

Critical Care (BioMed Central)

Year:

2011

Language:

english

File:

PDF, 80 KB

english, 2011

28

Effect of Standardized Surveillance of Intensive Care Unit–Acquired Infections on Ventilator-Associated Pneumonia Incidence

Bénet, Thomas, Ecochard, René, Voirin, Nicolas, Machut, Anaïs, Lepape, Alain, Savey, Anne, Vanhems, Philippe

Journal:

Infection Control and Hospital Epidemiology

Year:

2014

Language:

english

File:

PDF, 229 KB

english, 2014

29

ECDC definitions and methods for the surveillance of healthcare-associated infections in intensive care units

Plachouras, Diamantis, Lepape, Alain, Suetens, Carl

Journal:

Intensive Care Medicine

Year:

2018

Language:

english

File:

PDF, 720 KB

english, 2018

30

Cytokines et métabolisme protéique

Jacques Bienvenu, Laurence Coulon, Alain Lepape

Journal:

Nutrition Clinique et Métabolisme

Year:

1992

Language:

french

File:

PDF, 1002 KB

french, 1992

31

Estimating Attributable Mortality Due to Nosocomial Infections Acquired in Intensive Care Units •

Januel, Jean‐Marie, Harbarth, Stephan, Allard, Robert, Voirin, Nicolas, Lepape, Alain, Allaouchiche, Bernard, Guerin, Claude, Lehot, Jean‐Jacques, Robert, Marc‐Olivier, Fournier, Gérard

Journal:

Infection Control and Hospital Epidemiology

Year:

2010

Language:

english

File:

PDF, 231 KB

english, 2010

32

Identification of CD177 as the most dysregulated parameter in a microarray study of purified neutrophils from septic shock patients

Demaret, Julie, Venet, Fabienne, Plassais, Jonathan, Cazalis, Marie-Angélique, Vallin, Hélène, Friggeri, Arnaud, Lepape, Alain, Rimmelé, Thomas, Textoris, Julien, Monneret, Guillaume

Journal:

Immunology Letters

Year:

2016

Language:

english

File:

PDF, 1.94 MB

english, 2016

33

Fate and distribution of radioactive sodium diethyldithiocarbamate (Imuthiol®) in the mouse

Jean-Maurice Guillaumin, Alain Lepape, Gérard Renoux

Journal:

International Journal of Immunopharmacology

Year:

1986

Language:

english

File:

PDF, 1.01 MB

english, 1986

34

Early- and late-onset ventilator-associated pneumonia acquired in the intensive care unit: comparison of risk factors

Marine Giard, Alain Lepape, Bernard Allaouchiche, Claude Guerin, Jean-Jacques Lehot, Marc-Olivier Robert, Gérard Fournier, Didier Jacques, Dominique Chassard, Pierre-Yves Gueugniaud, François Artru, P

Journal:

Journal of Critical Care

Year:

2008

Language:

english

File:

PDF, 262 KB

english, 2008

35

Nosocomial Infection After Septic Shock Among Intensive Care Unit Patients •

Landelle, Caroline, Lepape, Alain, Français, Adrien, Tognet, Eve, Thizy, Hélène, Voirin, Nicolas, Timsit, Jean François, Monneret, Guillaume, Vanhems, Philippe

Journal:

Infection Control and Hospital Epidemiology

Year:

2008

Language:

english

File:

PDF, 240 KB

english, 2008

36

Decreased T-Cell Repertoire Diversity in Sepsis

Venet, Fabienne, Filipe-Santos, Orchidée, Lepape, Alain, Malcus, Christophe, Poitevin-Later, Françoise, Grives, Audrey, Plantier, Nadia, Pasqual, Nicolas, Monneret, Guillaume

Journal:

Critical Care Medicine

Year:

2013

Language:

english

File:

PDF, 660 KB

english, 2013

37

Agression et nutrition artificielle

Paul Boulétreau, Alain Lepape

Journal:

Nutrition Clinique et Métabolisme

Year:

1991

File:

PDF, 1.49 MB

1991

38

Postoperative infectious complications in paediatric liver transplantation: a study of 48 transplants

Jean-Christophe Bouchut, Didier Stamm, Olivier Boillot, Alain Lepape, Daniel Floret

Journal:

Pediatric Anesthesia

Year:

2001

Language:

english

File:

PDF, 77 KB

english, 2001

39

Étude multicentrique, randomisée, contrôlée, ouverte comparant 4 stratégies de préparation cutanée dans la prévention des infections de cathéters (ILC) acquises en réanimation

Mimoz, Olivier, Lucet, Jean-Christophe, Lepape, Alain, Timsit, Jean-François, Debaene, Bertrand

Journal:

Anesthésie & Réanimation

Year:

2015

Language:

french

File:

PDF, 146 KB

french, 2015

40

Concentrations plasmatiques des cytokines monocytaires et paramètres hormono-métaboliques au cours des états septiques et du choc septique

Alain Lepape, Jacques Bienvenu, Jean-Pierre Perdrix, Yves Barbier, Christophe Doche, Jean-Michel Grozel, Vincent Banssillon

Journal:

Nutrition Clinique et Métabolisme

Year:

1991

File:

PDF, 428 KB

1991

41

Effects of hydroxyethylstarch infusion on drug protein binding in critically ill patients

Jean-Christophe Bouchut, Alain Lepape, Pierre-Yves Carry

Journal:

European Journal of Anaesthesiology

Year:

2001

Language:

english

File:

PDF, 33 KB

english, 2001

42

Mesure de la culture sécurité : utilisation du Safety Attitudes Questionnaire en réanimation (SAQ-ICU)

Thiolliere, Fabrice, Ledochowski, Stanislas, Reynaud, Benoît, Wallet, Florent, Schaff, Barbara, Bohe, Julien, Piriou, Vincent, Lepape, Alain

Journal:

Anesthésie & Réanimation

Year:

2016

File:

PDF, 175 KB

2016

43

Both percentage of γδ T lymphocytes and CD3 expression are reduced during septic shock

Venet, Fabienne, Bohé, Julien, Debard, Anne-Lise, Bienvenu, Jacques, Lepape, Alain, Monneret, Guillaume

Journal:

Critical Care Medicine

Year:

2005

Language:

english

File:

PDF, 807 KB

english, 2005

44

Cost-effectiveness analysis of chlorhexidine-alcohol versus povidone iodine-alcohol solution in the prevention of intravascular-catheter-related bloodstream infections in France

Maunoury, Franck, Farinetto, Christian, Ruckly, Stéphane, Guenezan, Jeremy, Lucet, Jean-Christophe, Lepape, Alain, Pascal, Julien, Souweine, Bertrand, Mimoz, Olivier, Timsit, Jean-François, Puebla, Ir

Journal:

Year:

2018

Language:

english

File:

PDF, 2.21 MB

english, 2018

45

Fast renal trapping of porcine Luteinizing Hormone (pLH) shown by123I-scintigraphic imaging in rats explains its short circulatory half-life

Danièle Klett, Serge Bernard, François Lecompte, Hervé Leroux, Thierry Magallon, Alain Locatelli, Alain Lepape, Yves Combarnous

Journal:

Reproductive Biology and Endocrinology

Year:

2003

Language:

english

File:

PDF, 2.11 MB

english, 2003

46

Flow cytometric evaluation of lymphocyte transformation test based on 5-ethynyl-2′deoxyuridine incorporation as a clinical alternative to tritiated thymidine uptake measurement

Poujol, Fanny, Monneret, Guillaume, Friggeri, Arnaud, Rimmelé, Thomas, Malcus, Christophe, Poitevin-Later, Françoise, Pachot, Alexandre, Lepape, Alain, Textoris, Julien, Venet, Fabienne

Journal:

Journal of Immunological Methods

Year:

2014

Language:

english

File:

PDF, 764 KB

english, 2014

47

Proatrial natriuretic peptide is a better predictor of 28-day mortality in septic shock patients than proendothelin-1

Guignant, Caroline, Venet, Fabienne, Voirin, Nicolas, Poitevin, Françoise, Malcus, Christophe, Bohé, Julien, Lepape, Alain, Monneret, Guillaume

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2010

Language:

english

File:

PDF, 240 KB

english, 2010

48

The anti-inflammatory response dominates after septic shock: association of low monocyte HLA-DR expression and high interleukin-10 concentration

Guillaume Monneret, Marie-Emmanuelle Finck, Fabienne Venet, Anne-Lise Debard, Julien Bohé, Jacques Bienvenu, Alain Lepape

Journal:

Immunology Letters

Year:

2004

Language:

english

File:

PDF, 92 KB

english, 2004

49

Compliance With Guidelines on Antibiotic Prophylaxis in Total Hip Replacement Surgery: Results of a Retrospective Study of 416 Patients in a Teaching Hospital •

Pierrick Bedouch, PharmD, José Labarère, MD, Emmanuel Chirpaz, MD, Benoit Allenet, PharmD, PhD, Alain Lepape, MD, Magali Fourny, Patricia Pavese, MD, Pierre Girardet, MD, PhD, Philippe Merloz, MD, PhD

Journal:

Infection Control and Hospital Epidemiology

Year:

2004

Language:

english

File:

PDF, 138 KB

english, 2004

50

Delayed increase of S100A9 mRNA predicts hospital-acquired infection after septic shock

Fontaine, Mathieu, Pachot, Alexandre, Larue, Audrey, Mougin, Bruno, Landelle, Caroline, Venet, Fabienne, Allombert, Caroline, Cazalis, Marie-Angélique, Monneret, Guillaume, Lepape, Alain

Journal:

Critical Care Medicine

Year:

2011

Language:

english

File:

PDF, 507 KB

english, 2011

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